Romanian Journal of Infectious Diseases Logo
  • Home
  • Aims & Scope
  • Standards
    • Editorial policies
    • Instructions for authors
    • Peer review process
    • Guidelines for Reviewers
    • Ethics and Malpractice policies
    • Official Journal’s protocols & statements
    • Open Access
    • Fees
  • Editorial Council
  • Peer Review Council
  • EMC | CME
  • How to
  • SUBSCRIBE
  • Menu

Arhiva autor

  • About
  • Latest Posts

Cristina Voinea

Latest posts by Cristina Voinea (see all)

  • EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS - 25/01/2017
  • SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION - 25/01/2017
  • NIVELUL BNP (POLIPEPTIDUL NATRIURETIC TIP B) IN EXACERBARILE INFECTIOASE ALE BRONHOPNEUMOPATIEI CRONICE OBSTRUCTIVE - 25/08/2015

Articole semnate de acelasi autor in Revista Romana de Boli Infectioase:

EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XIX, No. 3, Year 2016
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS

Marilena Constantin, Mădălina Neața, Liliana Ștefan, Eliza Acatrinei, Aurelia Bumbu, Mihai Enyedi, Maria Nica, Cristina Voinea and Petre Calistru

REZUMAT

Streptococcus gallolyticus, membru al grupului Streptococcus bovis (strepococ de grup D) colonizează tubul digestiv al păsărilor, animalelor rumegătoare şi om (2,5-15%). Este descrisă în literatură asocierea bacteriemiei cu Streptococcus gallolyticus cu tumori colonice şi manifestări extracolonice (endocardită bacteriană, osteomielită vertebrală, discită, colangite, tumori pulmonare, ovariene).
Raportăm cazul unui pacient în vârstă de 60 ani, sex masculin, caucazian, la care infecţia cu Streptococcus Gallolyticus identificată prin hemocultură a avut ca primă manifestare osteomielită vertebrală.
S-au identificat leziuni la nivelul valvei aortice (endocardită bacteriană), arterei politee dreapta (tromboză diagnosticată prin ecografie Doppler artere, angio CT membre pelvine), genunchi drept (artrită). Deşi evoluţia a fost favorabilă din punct de vedere clinic (afebrilitate, ameliorarea durerii lombare) şi biologic (scăderea leucocitozei, a sindromului inflamator, hemoculturile ulterioare au fost negative) repetarea investigaţiilor imagistice la 30 zile şi la 45 zile au arătat insuficienţă aortică severă ce a necesitat intervenţie chirurgicală pentru înlocuire de valvă aortică efectuată la 2 luni de la diagnostic. Leziunile de la nivelul coloanei vetebrale, arterei poplitee s-au ameliorat după 2 luni de tratament antibiotic. Colonoscopia efectuată la 6 săptămîni de la diagnostic a arătat prezenţa polipilor colonici – posibilă poartă de intrare pentru Streptococcus gallolyticus.
Cazul prezentat demonstrează debutul silenţios al infecţiei cu Streptococcus gallolyticus, evoluţia ulterioară severă din cauza multiplelor determinări septice şi atrage atenţia asupra necesităţii efectuării explorărilor digestive (endoscopie digestivă superioară, colonoscopie) la pacienţii diagnosticaţi cu acest tip de infecţies.

Cuvinte cheie: Infecţie cu Streptococcus gallolyticus, osteomielită vertebrală, endocardită, tromboză

Full text | PDF

SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XIX, No. 3, Year 2016
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION

Marilena Constantin, Mădălina Neața, Liliana Ștefan, Eliza Acatrinei, Aurelia Bumbu, Mihai Enyedi, Maria Nica, Cristina Voinea and Petre Calistru

ABSTRACT

Streptococcus gallolyticus, member of streptococcus bovis group colonizes digestive tubes of birds, cows and human (2.5-15%). Literature describes the association between bacteriemia with Streptococcus gallolyticus and colon tumours but also extracolonic lesions (bacterial endocarditis, vertebral osteomyelitis, dyscitis, colangitis, lung tumors, ovarian tumors).
We report the case of a 60 years old male caucasian patient who was diagnosed with vertebral osteomyelitis as the first lesion of Streptococcus gallolyticus infection identified by blood culture. Other lesions were diagnosed on aortic valve (bacterian endocarditis), right popliteal artery (popliteal artery thrombosis), right knee (arthritis). Even if there was a clinical and biological improvement during the treatment, the imaging tests done after 30 and 45 days from the diagnosis showed severe aortic insuficiency so surgical intervention for aortic valvuloplasty was done in a short time. Vertebral and popliteal artery lesions have improved within two months of antibiotic treatment. Colonoscopy, which was done 6 weeks from the diagnosis showed colonic polyps – risk factors of Streptococcus gallolyticus bacteriemia.
This case proves that Streptococcus gallolyticus infection has a silent period followed by severe evolution by multiple septic lesions inspite of the precocious treatment and warn of the necessity of digestive investigations at these patients.

Keywords: Streptococcus Gallolyticus infection, vertebral osteomyelitis, endocarditis, thromboses

Full text | PDF

NIVELUL BNP (POLIPEPTIDUL NATRIURETIC TIP B) IN EXACERBARILE INFECTIOASE ALE BRONHOPNEUMOPATIEI CRONICE OBSTRUCTIVE

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XV, No. 2, Year 2012
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

NIVELUL BNP (POLIPEPTIDUL NATRIURETIC TIP B) IN EXACERBARILE INFECTIOASE ALE BRONHOPNEUMOPATIEI CRONICE OBSTRUCTIVE

Simona Ştefania Bucşa, Cristina Voinea and Petre Iacob Calistru

REZUMAT

Exacerbările bronhopneumopatiei cronice obstructive (BPOC) reprezintă o perioadă din evoluţia naturală a bolii, influenţând, prin frecvenţa şi severitatea lor, prognosticul vital al pacientului cu BPOC. Este şi motivul pentru care ultimele cercetări s-au concentrat asupra unor indicatori de prognostic la pacienţii cu exacerbări BPOC. Polipeptidul natriuretic tip B (Brain natriuretic polypeptide BNP) se consideră că poate reprezenta un marker noninvaziv util ca parametru predictor şi prognostic al exacerbării BPOC, noi informaţii şi rezultate în această direcţie fiind în beneficiul pacienţilor.

Cuvinte cheie: exacerbările bronhopneumopatiei cronice obstructive, infecţii bronhopulmonare, BNP (Polipeptidul natriuretic tip B)

Full text | PDF

DISTRIBUTIA GENOTIPURILOR HPV IN NEOPLAZIILE CERVICALE INTRAEPITELIALE – EXPERIENTA CDT „VICTOR BABES“

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XV, No. 4, Year 2012
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

DISTRIBUTIA GENOTIPURILOR HPV IN NEOPLAZIILE CERVICALE INTRAEPITELIALE – EXPERIENTA CDT „VICTOR BABES“

Claudia Ştefănescu, Petre Calistru, Cristina Voinea and George Gherlan

REZUMAT

Obiectiv. Studiul şi-a propus să evalueze efectul infecţiei cu serotipuri HPV cu risc înalt oncogen, singure sau în asociere, în prevalenţa şi severitatea neoplaziilor cervicale intraepiteliale (CIN) la pacientele din CDT „Victor Babeş“.

Material şi metodă. Au fost investigate 36 de paciente cu infecţie cu serotipuri HPV cu risc înalt oncogen descoperite în CDT „Victor Babeş“ în perioada mai 2009- februarie 2012 (34 de luni), cu vârste între 20-55 ani.

Rezultate. Prevalenţa HPV 16 în leziunile cervicale intraepiteliale de grad inalt (CIN 2/3) a fost 36% (9/25). Infecţia cu serotipul HPV 16, singur sau în asociere, este semnificativ statistică în CIN 2/3, în special pentru grupa de vârstă 21-30 ani [odds ratio(OR) 12; 95% confidence interval (CI) :0,9550-150,8]. Prevalenţa HPV 31 şi 52 în CIN 2/3 a fost 16% (4/25); pentru HPV 51 a fost 18,1% (4/22) în CIN 1.

Discuţii. În studiul nostru cele mai frecvente serotipuri cu risc înalt oncogen întâlnite au fost 16, 31, 52 şi 51. Serotipurile HPV cu risc înalt oncogen sunt întâlnite în toate gradele de leziuni preneoplazice, chiar şi în cazul pacientelor cu citologie normală.

Cuvinte cheie: serotipuri HPV cu risc înalt oncogen, prevalenţa HPV, leziuni cervicale

Full text | PDF

MODIFICARI ALE NIVELULUI SERIC DE BNP (POLIPEPTID NATRIURETIC TIP B) ASOCIATE EXACERBARILOR BRONHOPNEUMOPATIEI CRONICE OBSTRUCTIVE

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XVI, No. 3, Year 2013
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

MODIFICARI ALE NIVELULUI SERIC DE BNP (POLIPEPTID NATRIURETIC TIP B) ASOCIATE EXACERBARILOR BRONHOPNEUMOPATIEI CRONICE OBSTRUCTIVE

Simona Ştefania Bucşa, Petre Iacob Calistru and Cristina Voinea

REZUMAT

Introducere. Exacerbările bronhopneumopatiei cronice obstructive (BPOC) reprezintă principalele evenimente în evoluţia bolii care influenţează prin frecvenţa şi severitatea lor, prognosticul vital al pacientului. Impactul exacerbărilor frecvente ale bolii se manifestă prin declin rapid al funcţiei pulmonare, scăderea calităţii vieţii, creşterea inflamaţiei căilor aeriene şi mortalitate înaltă, motiv pentru care ultimele cercetări s-au concentrat asupra unor indicatori de prognostic la pacienţii cu exacerbări BPOC. BNP (Polipeptid natriuretic tip B) este secretat în principal de ventriculi, ca răspuns la supraîncărcarea de volum determinat în principal de insuficienţa cardiacă.

Scopul urmărit a fost de a preciza implicaţiile fiziopatologice şi importanţa practică a determinării şi monitorizării nivelului seric BNP corelate cu prezenţa exacerbărilor la pacienţii cu bronhopneumopatie cronică obstructivă.

Material şi metode. Cercetarea a inclus 84 pacienţi diagnosticaţi cu BPOC stabil conform criteriilor GOLD, fără semne şi simptome de hipertensiune pulmonară şi un lot martor de 70 de subiecţi sănătoşi. Studiul a fost prospectiv, s-a desfăşurat în CDT „Dr. Victor Babeş“, în perioada nov. 2011-dec. 2012. La vizita iniţială, pacienţii au fost examinaţi anamnestic şi clinic, prin spirometrie, ecocardiografie, determinarea BNP seric şi apoi au fost monitorizaţi urmărindu-se exacerbările şi relaţia cu nivelul seric al BNP. Pentru comparaţia între grupuri s-a folosit testul t-student şi test Mann Whitney U, iar diferenţele de la p < 0,05 au fost considerate semnificative.

Rezultate. Nivelul BNP plasmatic la pacienţii cu BPOC (51,0 ± 6,6 pg/ml) a fost semnificativ mai mare decât la subiecţii normali (24,2 ± 2,7 pg/ml) (p < 0,0001). Concentraţiile plasmatice de BNP la subiecţii cu BPOC stabil care au avut istoric de exacerbări cu spitalizare (67,2 ± 17,6 pg/ml) au fost semnificativ mai mari faţă de cei care nu au avut (28,3 ± 4,5 pg/ml) (p = 0,0039). Nivelul seric al BNP în timpul perioadelor de exacerbare (91,3 ± 17,3 pg/ml) a fost semnificativ mai mare decât în perioada de stabilitate a boli (52,6 ± 9,4 pg/ml) (p = 0,004) şi concentraţiile plasmatice de BNP în timpul exacerbărilor severe au fost mai mari, comparativ cu episoadele de exacerbare uşoare şi moderate (p < 0,001). Pacienţii care au necesitat spitalizare în timpul exacerbării (> 2 episoade/an) au înregistrat un nivel BNP semnificativ mai mare (102,3 ± 6,7) faţă de cei care au fost trataţi în ambulatoriu (73,6 ± 8,1) (p = 0,004).

Concluzii. Se consideră că Polipeptidul natriuretic tip B poate reprezenta un biomarker util pentru managementul pacienţilor cu exacerbare BPOC.

Cuvinte cheie: exacerbare bronhopneumopatie cronică obstructivă, BNP (Polipeptidul natriuretic tip B), biomarker

Full text | PDF

THE INTRA-OBSERVER VARIABILITY OF ACOUSTIC RADIATION FORCE IMPULSE (ARFI) – IMPLICATIONS FOR THE USE OF THE METHOD IN MONITORING CHRONIC LIVER DISEASES

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XVI, No. 3, Year 2014
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

THE INTRA-OBSERVER VARIABILITY OF ACOUSTIC RADIATION FORCE IMPULSE (ARFI) – IMPLICATIONS FOR THE USE OF THE METHOD IN MONITORING CHRONIC LIVER DISEASES

George Sebastian Gherlan, Petre Iacob Calistru, Cristina Voinea and Cristian Szabo

ABSTRACT

Introduction and aims. Liver fibrosis is reversible if the cause is removed or it may progress otherwise. Noninvasive methods tend to replace liver biopsy for the assessment of liver fibrosis. There is an intra-observer variability for ARFI that has to be taken into account when this method is used for monitoring the evolution of a liver disease. We aimed to identify the level of variation between two ARFI results that reflects a real change in liver histology rather than this “normal” variability. Patients and methods. Two sets of 10 ARFI measurements were performed in 147 patients by the same observer and we computed the median and the interquartile range for each set. We assessed the variation between the two results as percentage of each result. Data regarding weight, height, age, etiology, biochemical and hematological test were collected. Results. The mean variation was of 9.84% ± 9.7%. The variability is reduced if we use IQR for validation (valid if IQR < 1/3 of the result), with a variation of 7.66% ± 7.09% in the group with both measurements valid versus 16.33% ± 13.03% in the group with at least one set invalid. ARFI was feasible in all patients ant we found an intra-observer intraclass correlation coefficient of 0.976. Conclusions. Only results with over 19.5% variation in plus or minus compared to a previous result should be considered to reflect the progression respectively regression of liver fibrosis. If IQR is used as a validation parameter, the variability is less than 15%.

Keywords: ARFI, intra-observer, hepatitis, liver fibrosis, monitoring, variability

Full text | PDF



SEARCH

STANDARDE

  • Instructions for AUTHORS
  • Peer review process

Submit article

Submit your article to the journal by using the form here:

Submit

Subscriptions

To receive the Ro Journal of Infectious Diseases click here:

SUBSCRIBE
Publicare
Abonare

plic-maileditor@rjid.com.ro

Subscribe to the Newsletter

Articles from the journal are licensed under a 
Creative Commons Attribution 4.0 International License

 Terms & Conditions

Open Access Statement

Publisher : AMALTEA Medical Publishing House

The intended audience of the site content is professionals from the medical and pharmaceutical community.
This site does not collect any personal data nor does it use cookies that might obtain such data from your browser. [ info ]
Agree
Contact

Submit ARTICLE
E-mail: editor@rjid.com.ro  |  Mobile: +4 0742.155.512, M-F 09.00-18.00 EET

SUBSCRIPTIONS
E-mail: info@amaltea.ro |  Mobile: +4 0742.155.511, M-F 09.00-18.00 EET