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Mihai Enyedi

Latest posts by Mihai Enyedi (see all)

  • EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS - 25/01/2017
  • SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION - 25/01/2017

Articole semnate de acelasi autor in Revista Romana de Boli Infectioase:

EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XIX, No. 3, Year 2016
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

EVOLUTIE SEVERA CU MULTIPLE DETERMINARI SEPTICE LA UN PACIENT DIAGNOSTICAT CU INFECTIE CU STREPTOCOCCUS GALLOLYTICUS

Marilena Constantin, Mădălina Neața, Liliana Ștefan, Eliza Acatrinei, Aurelia Bumbu, Mihai Enyedi, Maria Nica, Cristina Voinea and Petre Calistru

REZUMAT

Streptococcus gallolyticus, membru al grupului Streptococcus bovis (strepococ de grup D) colonizează tubul digestiv al păsărilor, animalelor rumegătoare şi om (2,5-15%). Este descrisă în literatură asocierea bacteriemiei cu Streptococcus gallolyticus cu tumori colonice şi manifestări extracolonice (endocardită bacteriană, osteomielită vertebrală, discită, colangite, tumori pulmonare, ovariene).
Raportăm cazul unui pacient în vârstă de 60 ani, sex masculin, caucazian, la care infecţia cu Streptococcus Gallolyticus identificată prin hemocultură a avut ca primă manifestare osteomielită vertebrală.
S-au identificat leziuni la nivelul valvei aortice (endocardită bacteriană), arterei politee dreapta (tromboză diagnosticată prin ecografie Doppler artere, angio CT membre pelvine), genunchi drept (artrită). Deşi evoluţia a fost favorabilă din punct de vedere clinic (afebrilitate, ameliorarea durerii lombare) şi biologic (scăderea leucocitozei, a sindromului inflamator, hemoculturile ulterioare au fost negative) repetarea investigaţiilor imagistice la 30 zile şi la 45 zile au arătat insuficienţă aortică severă ce a necesitat intervenţie chirurgicală pentru înlocuire de valvă aortică efectuată la 2 luni de la diagnostic. Leziunile de la nivelul coloanei vetebrale, arterei poplitee s-au ameliorat după 2 luni de tratament antibiotic. Colonoscopia efectuată la 6 săptămîni de la diagnostic a arătat prezenţa polipilor colonici – posibilă poartă de intrare pentru Streptococcus gallolyticus.
Cazul prezentat demonstrează debutul silenţios al infecţiei cu Streptococcus gallolyticus, evoluţia ulterioară severă din cauza multiplelor determinări septice şi atrage atenţia asupra necesităţii efectuării explorărilor digestive (endoscopie digestivă superioară, colonoscopie) la pacienţii diagnosticaţi cu acest tip de infecţies.

Cuvinte cheie: Infecţie cu Streptococcus gallolyticus, osteomielită vertebrală, endocardită, tromboză

Full text | PDF

SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION

SELECT ISSUE

Romanian Journal of Infectious Diseases | Vol. XIX, No. 3, Year 2016
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJID has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

SEVERE EVOLUTION WITH MULTIPLE SEPTIC DETERMINATIONS IN A PATIENT DIAGNOSED WITH STREPTOCOCCUS GALLOLYTICUS INFECTION

Marilena Constantin, Mădălina Neața, Liliana Ștefan, Eliza Acatrinei, Aurelia Bumbu, Mihai Enyedi, Maria Nica, Cristina Voinea and Petre Calistru

ABSTRACT

Streptococcus gallolyticus, member of streptococcus bovis group colonizes digestive tubes of birds, cows and human (2.5-15%). Literature describes the association between bacteriemia with Streptococcus gallolyticus and colon tumours but also extracolonic lesions (bacterial endocarditis, vertebral osteomyelitis, dyscitis, colangitis, lung tumors, ovarian tumors).
We report the case of a 60 years old male caucasian patient who was diagnosed with vertebral osteomyelitis as the first lesion of Streptococcus gallolyticus infection identified by blood culture. Other lesions were diagnosed on aortic valve (bacterian endocarditis), right popliteal artery (popliteal artery thrombosis), right knee (arthritis). Even if there was a clinical and biological improvement during the treatment, the imaging tests done after 30 and 45 days from the diagnosis showed severe aortic insuficiency so surgical intervention for aortic valvuloplasty was done in a short time. Vertebral and popliteal artery lesions have improved within two months of antibiotic treatment. Colonoscopy, which was done 6 weeks from the diagnosis showed colonic polyps – risk factors of Streptococcus gallolyticus bacteriemia.
This case proves that Streptococcus gallolyticus infection has a silent period followed by severe evolution by multiple septic lesions inspite of the precocious treatment and warn of the necessity of digestive investigations at these patients.

Keywords: Streptococcus Gallolyticus infection, vertebral osteomyelitis, endocarditis, thromboses

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