National Awards “Science and Research”
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MATERNAL INFECTION WITH PARVOVIRUS B19 LEADING TO FETAL HYDROPS AND INTRAUTERINE DEATH – CASE PRESENTATION
Claudiu Mărginean, Lucian Pușcașiu, Claudiu Molnar Varlam and Rugină Cosmin
Parvovirus B19 belongs to the Parvoviridae family, Erythrovirus type, and it presents cytotoxicity on the erythroblast human line leading to severe anemia. We present the case of a 35-year-old woman, at the 3rd pregnancy, with a first trimester abortion in her history and a physiological birth, who presented to the specialty check-up at 20 gestational weeks, associating the signs of a respiratory infection, without any other pathologies until this gestational age. The laboratory tests and the fetal ultrasound did not point out any pathological elements, therefore the patient was sent home with the recommendation to come back after 2 weeks for reevaluation, when the fetal ultrasound revealed fetal hydrops and severe anemia, and after 24 hours fetal asystole. Maternal serology pointed out recent infection with Parvovirus B19. The particularity of this case consists in the appearance of relative rare fetal infection in the second trimester of pregnancy in the case of a physiological, monitored pregnancy, with unfavorable prognosis and fulminant death towards intrauterine death.
Keywords: maternal infection, Parvovirus B19, fetal hydrops, intrauterine death
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