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Romanian Journal of Infectious Diseases | Vol. XIX, No. 3, Year 2016
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

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HIV ASSOCIATED LYMPHOMA – TWO CASE REPORT SERIES

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ABSTRACT

Combined antiretroviral therapy significantly improved the prognosis and the life expectancy of HIV patients. Along with this, the profile of HIV associated malignant pathologies has changed. Among these,
lymphoma,with a higher incidence than in general population, are an important cause of mortality and morbidity in HIV infected people.
We present two cases of HIV-associated lymphoma. In the first case, a newly HIV diagnosed patient, with a good immunological status, developed non-Hodgkin´s Burkitt-type lymphoma and he had a fulminant evolution towards death. In the second case, a patient known for over twenty years with HIV infection and who had discordant immunological and virusological response to antiretroviral therapy, was diagnosed with Hodgkin´s lymphoma and he had a favorable evolution with chemotherapy. Both patients required exhaustive medical investigations and a close interdisciplinary cooperation during the entire time of diagnostic and therapeutic procedures.

Keywords: HIV, non-Hodgkin lymphoma, Hodgkin lymphoma

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