Romanian Journal of Infectious Diseases Logo
  • Home
  • Aims & Scope
  • Standards
    • Editorial policies
    • Instructions for authors
    • Peer review process
    • Guidelines for Reviewers
    • Ethics and Malpractice policies
    • Official Journal’s protocols & statements
    • Open Access
    • Fees
  • Editorial Council
  • Peer Review Council
  • EMC | CME
  • How to
  • SUBSCRIBE
  • Menu

Arhiva autor

  • About
  • Latest Posts

Cristina Nicolau

Latest posts by Cristina Nicolau (see all)

  • CHANGES IN THE CLINICAL AND EPIDEMIOLOGICAL PROFILE OF ACUTE HEPATITIS B IN THE INFECTIOUS DISEASES HOSPITAL OF IASI IN THE LAST 15 YEARS - 12/08/2015

Articole semnate de acelasi autor in Revista Romana de Boli Infectioase:

CHANGES IN THE CLINICAL AND EPIDEMIOLOGICAL PROFILE OF ACUTE HEPATITIS B IN THE INFECTIOUS DISEASES HOSPITAL OF IASI IN THE LAST 15 YEARS

SELECT ISSUE

Revista Romana de Boli Infectioase | Vol. XVI, No. 2, Year 2013
ISSN 1454-3389  |  e-ISSN 2069-6051
ISSN-L 1454-3389
DOI: 10.37897/RJID

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

CHANGES IN THE CLINICAL AND EPIDEMIOLOGICAL PROFILE OF ACUTE HEPATITIS B IN THE INFECTIOUS DISEASES HOSPITAL OF IASI IN THE LAST 15 YEARS

Andrei Vâţă, Mihaela Catalina Luca, Carmen Manciuc, Cristina Nicolau, Luminita Gina Vata and Carmen Mihaela Dorobat

ABSTRACT

Changes in the viral subtypes, in hygienic measures and the effects of the national vaccination program are factors that can influence the epidemiological and clinical features of acute hepatitis B. Material and methods. we retrospectively studied and compared two groups of patients diagnosed with acute hepatitis B in the Infectious Diseases Hospital of Iasi between 1997 and 2001 (group 1-582 cases) and between 2007 and 2011 (group 2-142 cases).

Results. Between the two intervals, the annual number of cases dropped by more than 4 times (p = 0.0006), the mean age of the patients has significantly increased (p < 0.001), as the proportion of those with rural origin (p = 0.003). Risk factors for the transmission of HBV were identified more frequently in the first group (p = 0.04). The maximum level of ALT has not changed, but a significant rise in the maximum level of total bilirubin was seen (p = 0.0004). The second group had a higher proportion of severe (p = 0.01) and prolonged (p = 0.04) forms of disease. Antiviral therapy was more common in the second group (p < 0.001), but the lethality was higher here too (p = 0.07).

Conclusions. The clinical and epidemiological profile of acute hepatitis B has significantly changed in the last 15 years, the decrease in the annual number of cases being paralleled by an increase of severe or cholestatic forms of disease

Key words: incidence, clinical form, cytolysis

Full text | PDF



SEARCH

STANDARDE

  • Instructions for AUTHORS
  • Peer review process

Submit article

Submit your article to the journal by using the form here:

Submit

Subscriptions

To receive the Ro Journal of Infectious Diseases click here:

SUBSCRIBE
Publicare
Abonare

plic-maileditor@rjid.com.ro

Subscribe to the Newsletter

Articles from the journal are licensed under a 
Creative Commons Attribution 4.0 International License

 Terms & Conditions

Open Access Statement

Publisher : AMALTEA Medical Publishing House

The intended audience of the site content is professionals from the medical and pharmaceutical community.
This site does not collect any personal data nor does it use cookies that might obtain such data from your browser. [ info ]
Agree
Contact

Submit ARTICLE
E-mail: editor@rjid.com.ro  |  Mobile: +4 0742.155.512, M-F 09.00-18.00 EET

SUBSCRIPTIONS
E-mail: info@amaltea.ro |  Mobile: +4 0742.155.511, M-F 09.00-18.00 EET